The researchers included a random selection of LBW infants at a gestation of less than 37 weeks or a birth weight of less than 2500g. The study used as many trials as possible. The infants were overall healthy and in a state of homeostasis, with no health conditions, and had been eligible to be transferred to intermediate care department of the NICU before the start of the intervention. “Trials generally excluded infants with congenital abnormalities, serious pathology (eg. necrotising enterocolitis), histories of maternal drug abuse and those requiring ventilatory assistance or intravenous feeding” (Vickers A. et al., p. 4) to eliminate or limit the independent variables as much as possible. The parents of the subjects studied were generally of low socioeconomic status. The trial used two categories for interventions: “gentle physical massage” and “gentle, still touch”. Infants receiving gentle physical massage were typically rubbed and stroked gently for approximately 15 minutes, three to four times a day. Many massage interventions also included kinesthetic stimulation consisting of passive flexion/extension movements of the limbs. Still, gentle touch involved nurses placing their hands on the infants as they slept. After 15 to 20 minutes they removed their hands. No stroking or rubbing motions were used. Both types of therapy were applied for 5-10 days. The results measured the advantages and disadvantages of massage on weight gain, length of hospital stay, and behavioral and developmental changes. The length of massage therapy applied to the infants was based on the number of days they stayed at the hospital and the data that was recorded. We felt that although the selection criteria was pretty simple and the design of the selection made it easier to eliminate unexpected variables in the study, 5-10 days of therapy does not seem to be a significant amount of time in order to produce results. There was no evidence of a correlation between infants who got a shorter massage and the ones who received longer duration. It is important to note that recording the data directly during the hospital stay of the infant, would eliminate many unknown variables that would otherwise affect the results of the study. Research MethodsWe the significant data we focused on were weight gain and length of stay in the hospital. The study also recorded developmental and behavioural outcomes using the Brazleton 1983, which is a standard developmental measure. The weight was measured daily using the hospital scale. No trial described procedures to blind those taking weight measurements. Nonetheless, poor blinding of the main outcome measure might be considered to be a flaw of the research included in the review. Also, there is an independent variable of caloric intake by the infants that affects the weight gain directly. The kind of nutrition the infants received, whether or not the infants were breastfed, nor the type of formula they received, were documented within the research study. The other significant value was the hospital stay, which was reported as significantly reduced to 4-5 days. But only one study (White Traut 1986 (Links to an external site.)Links to an external site.) of the two studies explicitly stated that physicians responsible for discharging infants were blind to group assignment. However, it is unclear how this blinding was achieved. Study Findings and LimitationsThe findings show that massage interventions resulted in improved daily weight gain by 5 grams and reduced length of stay by 4.5 days. Although there were no negative effects shown, the results of the benefits of massage on developmental outcome of preterm infants were weak. Researchers could not conclude that it doesn’t warrant wider use of massage as a treatment for preterm infants. The limitations consist of methodological issues when analyzing the results. For example, performance bias was not thoroughly observed to ensure each treatment was similar for the infants. Thus, it is important to consider that there may be differences in care due to the difficulty of creating a blind study. It is clear that more research should be done, because there were no significant outcomes specifying the effectiveness of massage therapy for LBW infants. Also, data recording and performance bias affected the results. Because the results do not seem to be significant, there is question whether health care personnel should invest time in performing the therapy. Relevance of StudyThis study emphasizes the importance of a less invasive non-pharmaceutical treatment option to promote weight gain for LBW infants. Massage therapy is a low-risk affordable therapy that is easy to implement in many settings in order to promote growth and health to at-risk infants. This therapy requires very little training and is able to be performed by non-licensed individuals such as caregivers. Based on the studies performed, there are no adverse effects of massage therapy for premature/LBW infants, nor are there significant benefits to massage therapy.